Wayne State Department of Emergency Medicine secures $ 15.88 million from CDC to study surveillance for viral infections

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Newswise – DETROIT – The United States Centers for Disease Control and Prevention awarded $ 15.88 million to the emergency medicine department at Wayne State University School of Medicine to be the epicenter of a national study on viral infections present in county emergency departments.

The “Enhancing US Surveillance of Laboratory Confirmed SARS-CoV-2, Influenza, and Other Respiratory Viruses through a Network of Emergency Departments” project will continue for three years.

Jeffrey Kline, MD, professor and associate chair of research for the Department of Emergency Medicine, is the overall principal investigator for the project, which will span emergency departments in 21 states and the District of Columbia, and 100 hospitals for surveillance of viral infections. . Data will be obtained from electronic medical records of participating hospital systems. Each participating system will receive a portion of the $ 15.88 million and have a principal investigator on site.

The project will now run until August 2024. “If we are successful at the end of the third year, we hope this will be repeated for years to come,” said Dr Kline.

The study is based on the Emergency Care COVID-19 Suspected Registry, or RECOVER, a large clinical registry of patients from 155 emergency departments in 27 states tested for SARS-CoV-2 from March to September 2020, which Dr Kline founded.

This study network will be called RECOVER-CDC.

Patients will be identified based on the reason or main complaint for their visit to the emergency department.

“We will report data on patients who primarily complain of viral syndromes, including, but not limited to cough, fever, muscle pain, sore throat, nasal congestion, and respiratory distress,” Dr Kline said. “We will then determine how many are tested for SARS-CoV-2, influenza, respiratory syncytial virus and other viruses as part of usual care and, most importantly, their vaccination status. We will then follow the patients to determine whether or not they are admitted to the hospital, and their results and diagnoses within 30 days.

The researchers aim to determine how often symptomatic patients are screened for viral infections, the results of these tests, the results and diagnoses of patients with known or suspected viral infections, and the associations between results and vaccination status.

“We will have a lot of other questions. For example, the association of viral infections with the diagnosis of blood clots is of key interest to my own research, ”said Dr. Kline.

The study team includes assistant vice president of research and professor of emergency medicine Phillip Levy, MD, as a co-investigator; professor of emergency medicine and director of biostatistics, epidemiology, and research design Core Robert Welch, MD, for analysis oversight; and EBRD Core statistician Liying Zhang, Ph.D., with initial support from the Director of Grant Management, Department of Emergency Medicine Lynn Marie Mango, MPH

The U.S. Centers for Disease Control and Prevention contract award number is 75D30121C11813.

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About Wayne State University

Wayne State University is one of the nation’s leading urban public research universities. Through its multidisciplinary approach to research and education and its continued collaboration with government, industry and other institutions, the university seeks to strengthen economic growth and improve the quality of life in the city. from Detroit, Michigan and around the world. For more information on research at Wayne State University, visit research.wayne.edu.


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